The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 25, 2018

Filed:

Jul. 13, 2012
Applicants:

Patricia D. Palena, Plainsboro, NJ (US);

Madiha Jafri, Mount Laurel, NJ (US);

Jason Poleski, Moorestown, NJ (US);

Sanipa K. Arnold, Huntingdon Valley, PA (US);

Inventors:

Patricia D. Palena, Plainsboro, NJ (US);

Madiha Jafri, Mount Laurel, NJ (US);

Jason Poleski, Moorestown, NJ (US);

Sanipa K. Arnold, Huntingdon Valley, PA (US);

Assignee:

LEIDOS INNOVATIONS TECHNOLOGY, INC., Gaithersburg, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01); A61B 5/00 (2006.01); A61B 5/053 (2006.01); A61B 5/1473 (2006.01); B01L 3/00 (2006.01); B82Y 15/00 (2011.01); B82Y 10/00 (2011.01); H01L 51/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/6847 (2013.01); A61B 5/0538 (2013.01); A61B 5/14735 (2013.01); B01L 3/502753 (2013.01); B82Y 10/00 (2013.01); B82Y 15/00 (2013.01); A61B 5/6865 (2013.01); A61B 2560/0285 (2013.01); A61B 2560/045 (2013.01); A61B 2560/0443 (2013.01); A61B 2562/028 (2013.01); A61B 2562/0285 (2013.01); A61B 2562/046 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0874 (2013.01); B01L 2300/0887 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0424 (2013.01); H01L 51/0049 (2013.01);
Abstract

A biosensor includes a microfluidics layer, a transduction layer and a transceiver layer. The transduction layer further includes a functionalized layer that reacts with a biomarker, and a plurality of carbon nanotubes adjacent the functionalized layer. The conductivity of the carbon nanotubes changes in response to a biomarker reacting with at least a portion of the functionalized layer. The functionalized layer can include dendrimers, such as a tadpole dendrimer scaffolding that includes a plurality of sites for receiving receptors for biomarkers.


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