The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2018
Filed:
Mar. 26, 2015
Applicants:
Academisch Medisch Centrum Bij DE Universiteit Van Amsterdam, Amsterdam, NL;
Aimm Therapeutics B.v., Amsterdam, Zuidoost, NL;
Inventor:
Hergen Spits, Amsterdam, NL;
Assignees:
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM, Amsterdam, NL;
AIMM THERAPEUTICS B.V., Amsterdam Zuidoost, NL;
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/06 (2006.01); C12N 5/0781 (2010.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0635 (2013.01); C07K 16/00 (2013.01); C12N 2501/23 (2013.01); C12N 2501/60 (2013.01);
Abstract
The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.