The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2018

Filed:

Dec. 25, 2014
Applicant:

National University Corporation Kochi University, Kochi-shi, Kochi, JP;

Inventors:

Tetsuji Naka, Osaka, JP;

Satoshi Serada, Osaka, JP;

Minoru Fujimoto, Osaka, JP;

Masayoshi Toyoura, Kyoto, JP;

Yuji Shoya, Kyoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61K 31/713 (2006.01); G01N 33/574 (2006.01); C12Q 1/6886 (2018.01); C07K 16/28 (2006.01); C12N 15/113 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 31/713 (2013.01); C07K 16/28 (2013.01); C12N 15/1138 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57407 (2013.01); A61K 2039/505 (2013.01); C07K 2317/23 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/705 (2013.01); G01N 2400/40 (2013.01);
Abstract

The present invention relates to an esophageal cancer marker and application thereof. The present invention relates to: a marker that includes Glypican-1 or an expression product thereof, or a fragment or derivative thereof, and serves to identify esophageal cancer; a detection agent that includes a substance that binds to Glypican-1 or an expression product thereof; and a composition that includes a Glypican-1 inhibitor and serves to prevent or treat esophageal cancer. Herein, Glypican-1 can be SEQ ID NO: 1 (nucleic acid sequence) or SEQ ID NO: 2 (amino acid sequence), or an equivalent thereof.


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