The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2018

Filed:

Jun. 12, 2017
Applicants:

Askgene Pharma Inc., Camarillo, CA (US);

Jiangsu Aosaikang Pharmaceutical Co., Ltd., Nanjing, CN;

Inventors:

Aijun Wang, Camarillo, CA (US);

Kurt Shanebeck, Camarillo, CA (US);

Donggou He, Camarillo, CA (US);

Chen Yao, Moorpark, CA (US);

Lu Li, Camarillo, CA (US);

Fang Xia, Camarillo, CA (US);

Yuefeng Lu, Newbury Park, CA (US);

Jian-Feng Lu, Oak Park, CA (US);

Lan Yang, Camarillo, CA (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention relates to compositions and methods for immunotherapy of a subject afflicted with diseases such as cancer, an infectious disease, or a neurodegenerative disease, which methods comprise administering to the subject a composition comprising a therapeutically effective amount of an anti-PD-L1 antibody or portion thereof that potentiates an endogenous immune response, either stimulating the activation of the endogenous response or inhibiting the suppression of the endogenous response.


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