The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2018
Filed:
Aug. 16, 2012
Applicants:
Bira Arya, Lutherville, MD (US);
Dan Longo, Kensington, MD (US);
Igor Espinoza-delgardo, Clarksville, MD (US);
Inventors:
Bira Arya, Lutherville, MD (US);
Dan Longo, Kensington, MD (US);
Igor Espinoza-Delgardo, Clarksville, MD (US);
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4748 (2013.01); A61K 39/0011 (2013.01); A61K 39/39 (2013.01); A61K 2039/55522 (2013.01); C07K 2319/33 (2013.01); C07K 2319/74 (2013.01);
Abstract
The instant invention provides compositions for the treatment of cancer. Specifically, the invention provides polypeptides and nucleic acid molecules comprising tumor-associated embryonic antigens, e.g., OFA-iLRP, and chemoattractant ligands, e.g., a proinflammatory chemokine such as MIP3α/CCL20 or β-defensin mDF2β. The invention further provides cancer vaccines and methods for treating subjects having, or at risk of developing, cancer.