The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2018
Filed:
Sep. 14, 2017
Applicant:
The Trustees of Princeton University, Princeton, NJ (US);
Inventors:
Joshua D. Rabinowitz, Princeton, NJ (US);
Hahn Kim, Princeton, NJ (US);
Gregory S. Ducker, Rocky Hill, NJ (US);
Jonathan M. Ghergurovich, Philadelphia, PA (US);
Assignee:
The Trustees of Princeton University, Princeton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/052 (2006.01); A61K 31/4162 (2006.01); A61K 31/19 (2006.01); A61K 31/496 (2006.01); A61K 31/198 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 491/052 (2013.01); A61K 31/19 (2013.01); A61K 31/198 (2013.01); A61K 31/4162 (2013.01); A61K 31/496 (2013.01); A61K 45/06 (2013.01);
Abstract
The disclosure provides compounds of Formulae (I)-(IX). The disclosed compounds are capable of inhibiting a mammalian SHMT. Compounds of the disclosure have numerous uses, such as for treatment of cancer or autoimmune disorders.