The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2018
Filed:
Mar. 06, 2015
Applicant:
Glactone Pharma Development Ab, Helsingborg, SE;
Inventors:
Martin Johansson, Peterborough, CA;
Olov Sterner, Malmö, SE;
Assignee:
Glactone Pharma Development AB, Helsingborg, SE;
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/93 (2006.01); A61K 31/365 (2006.01); A61K 38/05 (2006.01); A61K 38/06 (2006.01); C07K 5/02 (2006.01); C07K 5/062 (2006.01);
U.S. Cl.
CPC ...
C07D 307/93 (2013.01); A61K 31/365 (2013.01); A61K 38/05 (2013.01); A61K 38/063 (2013.01); C07K 5/0215 (2013.01); C07K 5/06052 (2013.01);
Abstract
Prodrugs (I) and (Ia) of galiellactone, and derivatives thereof, are provided by reacting the parent compound, e.g. galiellactone, with a thiol. Such drugs may be administered orally to treat cancer and other proliferative diseases.