The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2018
Filed:
Aug. 10, 2015
Chang Gung University, Taoyuan, TW;
Hao-Li Liu, Taoyuan, TW;
Kuo-Chen Wei, Taipei, TW;
Pin-Yuan Chen, Taoyuan, TW;
Po-Hung Hsu, Tainan, TW;
Po-Chun Chu, Taipei, TW;
Wen-Yen Chai, Taoyuan, TW;
Chung-Yin Lin, Kaohsiung, TW;
CHANG GUNG UNIVERSITY, Taoyuan, TW;
Abstract
Methods to use medical imaging to monitor the molecule penetration into CNS during ultrasound-mediated delivery are disclosed. The method states a two-step process to predict the amount of molecular penetration which is based on the observation of medical imaging. The first is to propose a unified exposure input to unify the exposure condition so as to build a transferred relation to imaging index. The second is to propose a unified imaging index to unify the imaging readout so as to build a reliable transferred relation to molecular concentration. Linking these two, the molecular penetration induced by ultrasound irradiation can be estimated from medical imaging with ultrasound exposure conditions and molecular sizes.