The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Jul. 23, 2015
Applicant:

Chu Sainte-justine, Montreal, CA;

Inventor:

Alain Moreau, Montreal, CA;

Assignee:

CHU SAINTE-JUSTINE, Montreal, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/533 (2006.01); G01N 33/536 (2006.01); G01N 33/541 (2006.01); G01N 33/68 (2006.01); A61K 33/04 (2006.01); A61F 5/01 (2006.01); A23L 33/00 (2016.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A23L 33/30 (2016.08); A61F 5/0102 (2013.01); A61K 33/04 (2013.01); G01N 33/6872 (2013.01); A23V 2002/00 (2013.01); G01N 2800/108 (2013.01); G01N 2800/50 (2013.01);
Abstract

A method for the prevention or treatment of scoliosis in a human subject comprising: (a)(i) measuring osteopontin (OPN) protein expression in a biological fluid sample from the subject over time; or (ii) measuring osteopontin (OPN) protein expression in a biological fluid sample from the subject and comparing the OPN protein expression to an OPN protein expression in a control biological fluid sample; (b) identifying the subject as being at risk of developing scoliosis when OPN protein expression increases in the subject sample over time; or when OPN protein expression is higher in the subject sample than that in the control sample; and (c) reducing OPN protein levels in the subject identified as being at risk of developing a scoliosis, thereby aiding in the prevention or treatment of scoliosis.


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