The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Apr. 28, 2015
Applicant:

Quest Diagnostics Investments Incorporated, Wilmington, DE (US);

Inventors:

Peter Lee, Tustin, CA (US);

Lakshmi Nair, Yorba Linda, CA (US);

Albert Castro, Walnut, CA (US);

Maria Vestal, Lakewood, CA (US);

Michelle Tabb, Santa Ana, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/70 (2006.01); C12P 19/34 (2006.01); C07H 21/04 (2006.01); G01N 1/30 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/701 (2013.01);
Abstract

Provided herein are methods for determining the presence or absence of an enteroviruses and parechoviruses in a biological sample. The methods involve identifying the presence or absence of a target nucleic acids from the viruses using direct amplification from a biological sample without a step of extraction of the nucleic acids, but retaining substantially the same specificity and sensitivity of methods assaying extracted nucleic acids. Also provided are methods of diagnosis using the methods provided and compositions and kits for the practice of the methods.


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