The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Jul. 10, 2014
Applicant:

Takara Bio Inc., Shiga, JP;

Inventors:

Shuhei Sakamoto, Kusatsu, JP;

Yasuhiro Kawano, Moriyama, JP;

Katsuyuki Dodo, Kusatsu, JP;

Tatsuji Enoki, Kyotanabe, JP;

Hirofumi Yoshioka, Rittou, JP;

Hikaru Takakura, Kyoto, JP;

Junichi Mineno, Uji, JP;

Assignee:

TAKARA BIO INC., Shiga, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 15/86 (2006.01); C12N 7/02 (2006.01); C12N 15/867 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C12N 2750/14151 (2013.01);
Abstract

The present invention provides a method for efficiently manufacturing a non-enveloped virus with high purity without laborious operation by cultivating cells having the ability to produce a non-enveloped virus and bringing the cells and an acidic solution into contact with each other. A non-enveloped virus vector manufactured by the method of the present invention and a composition having the non-enveloped viral vector as an active ingredient are very useful as gene transfer methods in the fields of basic research and clinical application gene therapy.


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