The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Dec. 03, 2015
Applicant:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Inventors:

Hongquan Wan, Rockville, MD (US);

Maryna C. Eichelberger, Silver Spring, MD (US);

Hua Yang, City Johns Creek, GA (US);

James Stevens, Lilburn, GA (US);

David A. Shore, Decatur, GA (US);

Rebecca J. Garten, Decatur, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); G01N 33/68 (2006.01); G01N 33/573 (2006.01); G01N 33/569 (2006.01); A61K 45/06 (2006.01); A61K 39/42 (2006.01); C07K 16/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1018 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); C07K 16/40 (2013.01); C12Y 302/01018 (2013.01); G01N 33/56983 (2013.01); G01N 33/573 (2013.01); G01N 33/6878 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/24 (2013.01); C07K 2317/54 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); G01N 2333/11 (2013.01); G01N 2333/924 (2013.01); G01N 2469/10 (2013.01);
Abstract

Isolated monoclonal antibodies and antigen binding fragments thereof that specifically bind neuraminidase (NA) of an N1 subtype influenza virus are disclosed herein. These antibodies and antigen binding fragments can be used for the detection of an N1 subtype influenza virus and for determining the immunogenicity of vaccines. The antibodies and antigen binding fragments also can be used for the treatment of a subject to prevent or ameliorate an influenza infection.


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