The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2018
Filed:
Jul. 06, 2017
Vib Vzw, Ghent, BE;
Universiteit Gent, Ghent, BE;
Centre National DE LA Recherche Scientifique, Paris, FR;
Université Montpellier 2, Montpellier, FR;
Centre Hospitalier Regional Universitaire DE Montpellier, Montpellier, FR;
Jan Tavernier, Balegem, BE;
Lennart Zabeau, Ghent, BE;
Gilles Uze, Montpellier, FR;
Franciane Paul, Montpellier, FR;
Yann Bordat, Montpellier, FR;
Genevieve Garcin, Montpellier, FR;
VIB VZW, Gent, BE;
UNIVERSITEIT GENT, Gent, BE;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
UNIVERSITÉ DE MONTPELLIER, Montpellier, FR;
CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE MONTPELLIER, Montpellier, FR;
Abstract
The present invention relates to a fusion protein, comprising a cytokine antagonist and a targeting moiety, preferably an antibody or anti-body like molecule. In a preferred embodiment, the cytokine antagonist is a modified cytokine which binds to the receptor, but doesn't induce the receptor signalling. The invention relates further to a fusion protein according to the invention for use in treatment of cancer and immune- or inflammation-related disorders.