The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2018
Filed:
Apr. 29, 2016
Emory University, Atlanta, GA (US);
Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);
Baozhong Wang, Dultuh, GA (US);
Richard W. Compans, Atlanta, GA (US);
Jacques Galipeau, Atlanta, GA (US);
Jiusheng Deng, Snellville, GA (US);
Emory University, Atlanta, GA (US);
Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);
Abstract
This disclosure relates to a GM-CSF and IL-4 conjugate fused to a glycolipid (GPI)-anchoring sequence that is incorporated into chimeric virus-like particles (VLPs) enriched with a viral protein, e.g., viral envelope protein or HIV envelope protein. In certain embodiments, the disclosure relates to methods of immunization with the chimeric VLPs disclosed herein. In certain embodiments, the disclosure relates to methods of immunization with disclosed HIV antigen containing VLPs through an intramuscular priming-intranasal boosting immunization route.