The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2018
Filed:
Dec. 14, 2016
Applicant:
Carnegie Mellon University, Pittsburgh, PA (US);
Inventors:
Krzysztof Matyjaszewski, Pittsburgh, PA (US);
Saadyah E. Averick, Pittsburgh, PA (US);
Antonina Simakova, Pittsburgh, PA (US);
Assignee:
CARNEGIE MELLON UNIVERSITY, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/107 (2006.01); C08G 81/02 (2006.01); C08F 283/06 (2006.01); C07K 14/435 (2006.01); C07K 14/765 (2006.01);
U.S. Cl.
CPC ...
C07K 1/1077 (2013.01); C07K 14/43595 (2013.01); C07K 14/765 (2013.01); C08F 283/06 (2013.01); C08G 81/025 (2013.01);
Abstract
Methods for conducting controlled grafting-from radical polymerizations from biomolecules under conditions that are biologically compatible are described. The methods provide biomolecule-polymer conjugates with highly controlled structures and narrow polydispersities under aqueous reaction conditions and biological temperatures. Biomolecules, such as proteins and nucleotides can be conjugated to polymers with high levels of control.