The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2018
Filed:
Jun. 18, 2014
Macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors
Applicant:
Cygnet Biosciences B.v., Willemstad, CW;
Inventors:
Stefania Sanfilippo, Siena, IT;
Brunella Posteraro, Rome, IT;
Maurizio Sanguinetti, Rome, IT;
Maurizio Botta, Siena, IT;
Giorgio Maccari, Siena, IT;
Filomena De Luca, Siena, IT;
Jean-Denis Docquier, Siena, IT;
Davide Deodato, Siena, IT;
Assignee:
CYGNET BIOSCIENCES B.V., Willemstad, CW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 273/00 (2006.01); C07D 413/04 (2006.01); C07C 279/24 (2006.01); A61K 31/395 (2006.01); A61K 31/4192 (2006.01); A61K 45/06 (2006.01); C07C 271/20 (2006.01);
U.S. Cl.
CPC ...
C07D 273/00 (2013.01); A61K 31/395 (2013.01); A61K 31/4192 (2013.01); A61K 45/06 (2013.01); C07C 271/20 (2013.01); C07C 279/24 (2013.01); C07D 413/04 (2013.01);
Abstract
The present invention relates to macrocyclic amidinourea derivatives of formula 8, methods of preparation and uses thereof, pharmaceutical compositions in particular to be used as chitinase inhibitors in the treatment of a fungal infection.