The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2018
Filed:
Nov. 08, 2017
Applicant:
Janssen Sciences Ireland Uc, Co Cork, IE;
Inventors:
Koen Vandyck, Paal-Beringen, BE;
Geerwin Yvonne Paul Haché, Kapellen, BE;
Bart Rudolf Romanie Kesteleyn, Berlare, BE;
Pierre Jean-Marie Bernard Raboisson, Rosieres, BE;
Assignee:
Janssen Sciences Ireland UC, Co Cork, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/08 (2006.01); C07D 211/14 (2006.01); A61K 31/40 (2006.01); A61K 31/445 (2006.01); C07D 207/16 (2006.01); A61K 45/06 (2006.01); A61K 31/4025 (2006.01); C07D 211/60 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 207/16 (2013.01); A61K 31/40 (2013.01); A61K 31/4025 (2013.01); A61K 31/445 (2013.01); A61K 45/06 (2013.01); C07D 211/60 (2013.01); C07D 405/12 (2013.01);
Abstract
Inhibitors of HBV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein, X, Rto Rhave the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.