The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Mar. 11, 2013
Applicant:

Colorado State University Research Foundation, Fort Collins, CO (US);

Inventors:

Susan P. James, Bellvue, CO (US);

Harold Dean, IV, Ventura, CA (US);

Lakshmi Prasad Dasi, Fort Collins, CO (US);

Marcio H. Forleo, Fort Collins, CO (US);

Ketul C. Popat, Fort Collins, CO (US);

Nicole R. Lewis, Fort Collins, CO (US);

David Alois Prawel, Loveland, CO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/48 (2006.01); A61F 2/24 (2006.01); A61L 27/18 (2006.01); A61L 27/20 (2006.01); A61L 27/54 (2006.01); A61L 27/16 (2006.01); A61L 27/50 (2006.01); A61L 29/12 (2006.01); A61L 29/14 (2006.01); A61L 31/12 (2006.01); A61L 31/14 (2006.01); A61L 17/10 (2006.01);
U.S. Cl.
CPC ...
A61L 27/48 (2013.01); A61F 2/24 (2013.01); A61L 17/10 (2013.01); A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/20 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61L 29/126 (2013.01); A61L 29/14 (2013.01); A61L 31/129 (2013.01); A61L 31/14 (2013.01); A61L 2300/236 (2013.01); A61L 2300/42 (2013.01); A61L 2300/62 (2013.01); A61L 2430/20 (2013.01);
Abstract

Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.


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