The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Jan. 15, 2015
Applicant:

Shenzhen Tailai Biopharmaceuticals, Llc, Shenzhen, Guangdong, CN;

Inventors:

Tao Bian, Jiangsu, CN;

Juan Li, Jiangsu, CN;

Xiao Xiao, Jiangsu, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/025 (2006.01); C07K 14/35 (2006.01); C07K 14/535 (2006.01); C07K 14/54 (2006.01); A61K 39/39 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 39/39 (2013.01); C07K 14/005 (2013.01); C07K 14/35 (2013.01); C07K 14/535 (2013.01); C12N 7/00 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6043 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/20022 (2013.01); C12N 2710/20034 (2013.01); C12N 2710/20071 (2013.01);
Abstract

An immunity enhancing therapeutic vaccine includes a gene vector based on recombinant adenovirus and three elements: 1) an HPV antigen including the E6 and E7 multivalent fusion proteins of HPV types 16 and 18, 2) an immunologic adjuvant protein fused with said antigen, which protein may be a heat shock protein (HSP) of, and 3) an immunostimulant, which may be granulocyte-macrophage colony stimulating factor (GM-CSF). The vaccine is used for the treatment of human papilloma virus infections and related diseases.


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