The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Jul. 30, 2013
Applicant:

United Therapeutics Corporation, Silver Spring, MD (US);

Inventors:

Roger Jeffs, Chapel Hill, NC (US);

Thomas Petersen, Durham, NC (US);

Roger M. Ilagan, Burlington, NC (US);

Michael Wade, Chapel Hill, NC (US);

Assignee:

United Therapeutics Corporation, Silver Spring, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 35/44 (2015.01); A61K 31/5585 (2006.01); C12N 5/0775 (2010.01); A61K 45/06 (2006.01); C12N 5/071 (2010.01); A61K 31/192 (2006.01); A61K 48/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/44 (2013.01); A61K 31/192 (2013.01); A61K 31/5585 (2013.01); A61K 35/28 (2013.01); A61K 45/06 (2013.01); C12N 5/0663 (2013.01); C12N 5/0692 (2013.01); A61K 48/005 (2013.01); A61K 2035/124 (2013.01); C12N 2501/02 (2013.01);
Abstract

The application is directed to a method for treating or preventing vasculopathy comprising administrating to a subject in need thereof a pharmaceutical composition comprising mesenchymal precursor cells (MPCs) and a prostacyclin. Also provided a method for treating or preventing vasculopathy in a subject in need thereof, comprising administering to the subject a prostacyclin and a mesenchymal stem cell (MSC) or a MSC-conditioned culture medium or administering to the subject a MSC or a MSC-conditioned culture medium that has treated with prostacyclin. Pharmaceutical compositions suitable for such treatments are also provided.


Find Patent Forward Citations

Loading…