The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Jan. 03, 2018
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Shubha Bagrodia, San Diego, CA (US);

Jennifer Lafontaine, San Diego, CA (US);

Zach Lovatt, Belmont, MA (US);

Eyoung Shin, Marlborough, MA (US);

Young Ho Song, Natick, MA (US);

Greg Troiano, Pembroke, MA (US);

Hong Wang, Newton, MA (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 31/5377 (2006.01); A61K 9/51 (2006.01); A61K 9/107 (2006.01); A61K 47/34 (2017.01); A61K 47/28 (2006.01); A61K 47/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 9/1075 (2013.01); A61K 9/5153 (2013.01); A61K 47/12 (2013.01); A61K 47/28 (2013.01); A61K 47/34 (2013.01);
Abstract

The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid and a therapeutic agent (1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea), or pharmaceutically acceptable salts thereof, and a polymer. Other aspects include methods of making and using such nanoparticles.


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