The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2018
Filed:
Jun. 27, 2016
Applicant:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Inventors:
Steven J. Kridel, Clemmons, NC (US);
W. Todd Lowther, Pfafftown, NC (US);
Herman H. Odens, Ooltewah, TN (US);
Jeffrey D. Schmitt, Asheville, NC (US);
Assignee:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/416 (2006.01); A61K 31/42 (2006.01); C07D 231/56 (2006.01); C07D 261/20 (2006.01);
U.S. Cl.
CPC ...
A61K 31/416 (2013.01); A61K 31/42 (2013.01); C07D 231/56 (2013.01); C07D 261/20 (2013.01);
Abstract
Active compounds useful for inhibiting fatty acid synthase in a subject in need thereof are described. The active compounds are, in general, a 5-mercapto-1H-Indazole-4,7-dione or an analog thereof. The compounds are useful for treating subjects afflicted with, cancer, obesity, diabetes, a viral infection, a bacterial infection, a fungal infection, or a protozoal infection.