The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

Aug. 21, 2017
Applicant:

Arena Pharmaceuticals, Inc., San Diego, CA (US);

Inventors:

Marlon Carlos, Chula Vista, CA (US);

Weitong Dong, Shanghai, CN;

Mark Macias, San Diego, CA (US);

Suzanne Michiko Sato, San Diego, CA (US);

Lee Alani Selvey, Poway, CA (US);

Assignee:

Arena Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 231/16 (2006.01); A61K 31/415 (2006.01); C07D 231/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/415 (2013.01); C07D 231/12 (2013.01); C07D 231/16 (2013.01);
Abstract

The present invention is directed to processes and intermediates useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea (Compound I), crystalline forms and solvate forms thereof; and compositions comprising 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea, crystalline forms and solvate forms thereof prepared by processes as described herein.


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