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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10071056 B1

PDFFull Text
Date of Patent:
Sep. 11, 2018

Filed:

Feb. 18, 2016

Cancer cell targeting using nanoparticles

Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Stephen E. Zale, Hopkinton, MA (US);

Mir Mukkaram Ali, Woburn, MA (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:

Richard V. Zanzalari

Primary Examiner:

Devang K Thakor

Assistant Examiner:

Ivan A Greene

Int. Cl.
CPC ...
B82Y 5/00 (2011.01); A61K 9/16 (2006.01); A61K 9/51 (2006.01); A61K 31/197 (2006.01); A61K 31/337 (2006.01); C07C 275/24 (2006.01); C08G 63/664 (2006.01); C07C 275/16 (2006.01); C08G 63/685 (2006.01); C08G 63/692 (2006.01); A61K 47/34 (2017.01); A61K 9/14 (2006.01); A61K 31/136 (2006.01); A61K 31/704 (2006.01); A61K 47/60 (2017.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 9/1647 (2013.01); A61K 9/146 (2013.01); A61K 9/5153 (2013.01); A61K 9/5192 (2013.01); A61K 31/136 (2013.01); A61K 31/197 (2013.01); A61K 31/337 (2013.01); A61K 31/704 (2013.01); A61K 47/34 (2013.01); A61K 47/542 (2017.08); A61K 47/60 (2017.08); A61K 47/6935 (2017.08); A61K 47/6937 (2017.08); B82Y 5/00 (2013.01); C07C 275/16 (2013.01); C07C 275/24 (2013.01); C08G 63/664 (2013.01); C08G 63/6852 (2013.01); C08G 63/6922 (2013.01); Y10S 977/904 (2013.01); Y10S 977/905 (2013.01); Y10S 977/906 (2013.01); Y10S 977/911 (2013.01); Y10S 977/915 (2013.01);
Abstract

The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. Other aspects of the invention are directed to methods using nanoparticle libraries.

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