The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2018

Filed:

May. 29, 2014
Applicants:

Peter Sutovsky, Columbia, MO (US);

Young-joo Yi, Columbia, MO (US);

Inventors:

Peter Sutovsky, Columbia, MO (US);

Young-Joo Yi, Columbia, MO (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 17/43 (2006.01); C12N 5/073 (2010.01); A01N 1/02 (2006.01); G01N 33/50 (2006.01); A61D 19/02 (2006.01); C12N 5/075 (2010.01); C12N 5/076 (2010.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61B 17/43 (2013.01); A01N 1/0226 (2013.01); A61D 19/02 (2013.01); C12N 5/061 (2013.01); C12N 5/0604 (2013.01); C12N 5/0609 (2013.01); C12N 5/0612 (2013.01); G01N 33/5005 (2013.01); C12N 2500/05 (2013.01); C12N 2517/10 (2013.01);
Abstract

The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst.


Find Patent Forward Citations

Loading…