The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2018

Filed:

Nov. 13, 2014
Applicant:

Acea Biosciences, Inc., San Diego, CA (US);

Inventors:

Yama A. Abassi, San Diego, CA (US);

Naichen Yu, San Diego, CA (US);

Josephine Atienza, San Diego, CA (US);

Xiao Xu, San Diego, CA (US);

Xiaobo Wang, San Diego, CA (US);

Assignee:

ACEA Biosciences, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12Q 1/00 (2006.01); G01N 27/02 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5041 (2013.01); C12Q 1/002 (2013.01); G01N 27/021 (2013.01); G01N 33/5014 (2013.01); G01N 33/5438 (2013.01); G01N 2333/4716 (2013.01); G01N 2333/705 (2013.01); G01N 2333/91205 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01);
Abstract

Use of cell-substrate impedance based methods for screening for agonists of G-Protein Coupled Receptors (GPCRs) or inhibitors of a Receptor Tyrosine Kinases (RTKs), identifying compounds that affect GPCR or RTK pathways, validating molecular targets involved in a GPCR or RTK signaling pathways, monitoring dose-dependent functional activation of GPCR or RTK; determining desensitization of a GPCR and identifying a compound capable of affecting RTK activity in cancer cell proliferation.


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