The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2018

Filed:

May. 29, 2015
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);

Inventors:

Stephen R. Quake, Palo Alto, CA (US);

Jianbin Wang, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 9/16 (2006.01); A61K 38/00 (2006.01); C12N 15/90 (2006.01); C12N 15/113 (2010.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 9/16 (2013.01); C12N 9/22 (2013.01); C12N 15/1133 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01); C12N 2310/20 (2017.05); C12N 2330/51 (2013.01); C12N 2810/60 (2013.01); C12Y 301/00 (2013.01);
Abstract

The invention provides delivery methods and compositions for antiviral therapeutics. Methods and compositions are provided for targeted delivery of antiviral therapeutics into cells of interest using, for example, viral vectors such as adenovirus, AAV, and replication incompetent HSV. These and other delivery systems can be used as vehicles to deliver DNA vectors encoding a nuclease or a cell-killing gene. These delivery methods can also be used to deliver naked DNA or RNA, protein products, plasmids containing a promoter that is active only in a latent viral state which drives a cell-killing gene, or other therapeutic agents.


Find Patent Forward Citations

Loading…