The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Jul. 28, 2016
Applicants:
Otonomy, Inc., San Diego, CA (US);
Horacio Uri Saragovi, Montreal, CA;
Inventors:
Horacio Uri Saragovi, Montreal, CA;
Fabrice Piu, San Diego, CA (US);
Assignee:
OTONOMY, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 31/7088 (2006.01); C12N 15/86 (2006.01); C12N 7/00 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 48/00 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61K 9/0046 (2013.01); A61K 9/06 (2013.01); A61K 31/7088 (2013.01); A61K 48/00 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2710/10043 (2013.01); C12N 2740/15043 (2013.01);
Abstract
Disclosed herein are methods, compositions, vectors, and kits comprising an antagonist of a truncated TrkC or a truncated TrkB. Also described herein are methods of treating and/or preventing an otic disease or condition associated with an elevated expression level of a truncated TrkC or truncated TrkB isoform.