The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Jul. 19, 2016
Seoul National University R&db Foundation, Seoul, KR;
Nano Intelligent Biomedical Engineering Corporation Co. Ltd., Chungcheongbuk-do, KR;
Yoon Jeong Park, Seoul, KR;
Chong-Pyoung Chung, Seoul, KR;
Jin Sook Suh, Seoul, KR;
Jue-Yeon Lee, Gyeonggi-do, KR;
Dong Woo Lee, Seoul, KR;
Seoul National University R&DB Foundation, Seoul, KR;
Nano Intelligent Biomedical Engineering Corporation Co. Ltd., Chungcheongbuk-do, KR;
Abstract
Provided is a method of preparing induced pluripotent stem cells using a synthetic peptide, and more particularly, to a method of preparing induced pluripotent stem cells using a peptide capable of inhibiting the activity of NF-κB and promoting mesenchymal-epithelial transition (MET). Since undifferentiated multipotent stem cells may be efficiently prepared under xenopathogen-free or feeder cell-free conditions without requiring co-culture with animal serum or xenogeneic cells, the method for preparing the induced pluripotent stem cells using the synthetic peptide according to the present disclosure is very useful for developing stem cell therapeutic agents that are clinically applicable.