The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Jan. 13, 2015
The Broad Institute, Inc., Cambridge, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Rijksuniversiteit Groningen, Groningen, NL;
Walter F. Mangel, Shoreham, NY (US);
Paul Blainey, Cambridge, MA (US);
Vito Graziano, West Babylon, NY (US);
Andreas Herrmann, Groningen, NL;
William J. McGrath, Wadding River, NY (US);
Antonius Martinus Van Oijen, Groningen, NL;
Xiaoliang Sunney Xie, Lexington, MA (US);
The Broad Institute Inc., Cambridge, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Rijksuniversiteit Groningen, CP Groningen, NL;
Abstract
The present invention relates to compositions which may comprise a molecular sled linked to cargo and uses thereof. In particular, the present invention relates to a non-naturally occurring or engineered composition which may comprise a molecular sled, linkers and a molecular cargo connected to the sled via the linkers. Methods involving the use of molecular sleds and their cargoes and pharmaceutical compositions, methods for treating cancer, a degenerative disease, a genetic disease or an infectious disease as well as diagnostic methods are also contemplated by the present invention.