The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Jun. 02, 2015
Amide derivatives of 1-oxa-4,9-diazaspiro undecane compounds having multimodal activity against pain
Laboratorios Del Dr. Esteve S.a., Barcelona, ES;
Marina Virgili-Bernado, Barcelona, ES;
Monica Alonso-Xalma, Barcelona, ES;
Carlos Alegret-Molina, Barcelona, ES;
Carmen Almansa-Rosales, Barcelona, ES;
Ramón Merce-Vidal, Barcelona, ES;
ESTEVE PHARMACEUTICALS S.A., Barcelona, ES;
Abstract
The present invention relates to compounds having dual pharmacological activity towards both the sigma (σ) receptor, and the μ-opiod receptor and more particularly to diazaspiro undecane compounds having this pharmacological activity, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain. whereinY is n is 1 or 2;q is 1, 2, 3, 4, 5 or 6;X is a bond, —C(O)O—, —C(O)NR—, —C(O)—, —O— or —C(RR)—;Ris C(O)Ror S(O)R.