The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2018

Filed:

May. 19, 2016
Applicants:

Deutsches Krebsforschungszentrum, Heidelberg, DE;

Ruprecht-karls-universität Heidelberg, Heidelberg, DE;

Inventors:

Michael Boutros, Heidelberg, DE;

Rajendra-Prasad Maskey, Heidelberg, DE;

Corinna Koch, Einhausen, DE;

Florian Fuchs, Weil am Rhein, DE;

Sandra Steinbrink, Eppstein, DE;

Daniel Gilbert, Heidelberg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/92 (2006.01); C07D 311/96 (2006.01); C07D 413/04 (2006.01); C07D 491/04 (2006.01); C07D 493/04 (2006.01); C07D 311/04 (2006.01); C07D 491/052 (2006.01);
U.S. Cl.
CPC ...
C07D 311/92 (2013.01); C07D 311/04 (2013.01); C07D 311/96 (2013.01); C07D 413/04 (2013.01); C07D 491/04 (2013.01); C07D 491/052 (2013.01); C07D 493/04 (2013.01);
Abstract

Compounds of formula (IIc); wherein Xand Xindependently from each other are N or CRwherein Rmay be same or different; Y, Y, Yand Yindependently from each other are N or CRwherein Rmay be same or different and wherein up to 3 of the group Y, Y, Yand Ymay be N; their solvates, hydrates, and pharmaceutically acceptable salts, their use for modulating the Wnt signalling pathway activity and their use as a medicament, preferably for the treatment of cancer.


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