The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2018

Filed:

Jul. 16, 2015
Applicant:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Inventors:

Changchung Cheng, Dongguan, CN;

Yingjun Zhang, Dongguan, CN;

Bing Liu, Dongguan, CN;

Bohua Long, Dongguan, CN;

Yu Chen, Dongguan, CN;

Zhixin Cheng, Dongguan, CN;

Assignee:

SUNSHINE LAKE PHARMA CO., LTD., Dongguan, Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 261/14 (2006.01); C07D 487/04 (2006.01); C07D 491/107 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01); C07D 513/04 (2006.01); C07D 519/00 (2006.01); A61K 31/5377 (2006.01); A61K 31/422 (2006.01); A61K 31/4439 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); C07D 491/056 (2006.01); A61K 31/496 (2006.01); A61K 31/454 (2006.01); C07D 491/08 (2006.01); A61K 31/4545 (2006.01); A61K 31/541 (2006.01); A61K 31/5025 (2006.01); A61K 31/437 (2006.01); C07D 513/14 (2006.01);
U.S. Cl.
CPC ...
C07D 261/14 (2013.01); A61K 31/422 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/5025 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); C07D 413/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/056 (2013.01); C07D 491/08 (2013.01); C07D 491/107 (2013.01); C07D 513/04 (2013.01); C07D 513/14 (2013.01); C07D 519/00 (2013.01);
Abstract

Provided herein are novel substituted urea derivatives, and pharmaceutical compositions thereof. Also provided herein are uses of the compounds or pharmaceutical compositions thereof for preventing, managing, treating or lessening a proliferative disease, and modulating the activity of protein kinase.


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