The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Nov. 29, 2016
Zhejiang Nhu Company Ltd., Shaoxing, Zhejiang Province, CN;
Shandong Nhu Pharmaceutical Co., Ltd., Weifang, Shandong Province, CN;
Zhejiang University, Hangzhou, Zhejiang Province, CN;
Yougui Zhou, Shaoxing, CN;
Ming Yu, Shaoxing, CN;
Jintao Yuan, Shaoxing, CN;
Lei Zhao, Shaoxing, CN;
Xiandong Zhu, Shaoxing, CN;
Guangxiong Yu, Shaoxing, CN;
Weiwei Su, Shaoxing, CN;
Weikang Shao, Shaoxing, CN;
Xingxing Shi, Shaoxing, CN;
Yin Zhang, Shaoxing, CN;
Ming Feng, Shaoxing, CN;
Zhirong Chen, Hangzhou, CN;
Haoran Li, Hangzhou, CN;
Yuhong Zhang, Hangzhou, CN;
ZHEJIANG NHU COMPANY LTD., Shaoxing, CN;
SHANDONG NHU PHARMACEUTICAL CO., LTD., Weifang, CN;
ZHEJIANG UNIVERSITY, Hangzhou, CN;
Abstract
The present invention discloses a method for preparing optically active carbonyl compound, comprising the following steps: under the catalysis of chiral amine salt and transition metal catalysts, with hydrogen and catalytic amount of dihydropyridine compound as hydrogen source, use α, β-unsaturated aldehydes or α, β-unsaturated troponoid compounds to conduct asymmetric catalytic reaction to obtain the optically active carbonyl compound. This method comes in moderate reaction condition, simple operation, and catalytic amount of dihydropyridine compounds usage, the target product is easy to be separated and purified from the reaction system, and the metal catalyst can be recycled, it is economical.