The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Mar. 23, 2013
Applicant:
Hanmi Science Co., Ltd, Hwaseong-si, Gyeonggi-do, KR;
Inventors:
Hyung Kyu Lim, Hwaseong-si, KR;
Hyun Uk Kim, Busan, KR;
Sung Hee Hong, Suwon-si, KR;
Sung Min Bae, Seongnam-si, KR;
Se Chang Kwon, Seoul, KR;
Assignee:
HANMI SCIENCE CO., LTD., Hwaseong-si, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/20 (2006.01); A61K 47/68 (2017.01); A61K 47/26 (2006.01); C07K 14/61 (2006.01); A61K 47/48 (2006.01); A61K 38/27 (2006.01); A61K 9/08 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48369 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 38/27 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); A61K 47/68 (2017.08); A61K 47/6811 (2017.08); C07K 14/61 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention relates to a liquid formulation of highly concentrated long-acting human growth hormone conjugate, comprising a pharmaceutically effective amount of the long-acting human growth hormone conjugate in which human growth hormone (hGH) is linked to an immunoglobulin Fc region, and an albumin-free stabilizer, said stabilizer comprising a buffer, a non-ionic surfactant, a sugar alcohol, and sodium chloride as an isotonic agent, and a method for preparing the same.