The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Nov. 23, 2015
Combination therapy using c-met inhibitor and igf-1r inhibitor for c-met inhibitor resistant cancers
Applicants:
Samsung Electronics Co., Ltd., Suwon-si, Gyeonggi-do, KR;
Yonsei University, University-industry Foundation (Uif), Seoul, KR;
Inventors:
Seon Hui Shim, Daejeon, KR;
Ji Min Lee, Seoul, KR;
Soo Yeon Jung, Seongnam-si, KR;
Woo Sun Kwon, Seoul, KR;
Kyung Ah Kim, Seongnam-si, KR;
Jeong Min Kim, Seoul, KR;
Sun Young Rha, Seoul, KR;
Won Suk Lee, Seoul, KR;
Assignees:
SAMSUNG ELECTRONICS CO., LTD., Suwon-si, KR;
YONSEI UNIVERSITY, UNIVERSITY-INDUSTRY FOUNDATION (UIF), Seoul, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/00 (2006.01); C07K 16/28 (2006.01); A61K 31/4985 (2006.01); G01N 33/574 (2006.01); G01N 33/74 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); A61K 31/00 (2013.01); A61K 31/4985 (2013.01); C07K 16/2863 (2013.01); G01N 33/57492 (2013.01); G01N 33/74 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/52 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); G01N 2333/65 (2013.01); G01N 2800/52 (2013.01);
Abstract
A method of preventing and/or treating a cancer, the method including co-administering a dual inhibitor of c-Met (hereinafter, 'c-Met inhibitor') and an IGF-1R inhibitor to a subject in need thereof and a use of IGF-1R as a marker for resistance to a c-Met inhibitor.