The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Oct. 08, 2012
Applicant:
The Research Foundation for the State University of New York, Amherst, NY (US);
Inventor:
Sathy V. Balu-Iyer, Amherst, NY (US);
Assignee:
The Research Foundation for The State University of New York, Amherst, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/37 (2006.01); A61K 9/127 (2006.01); A61K 38/47 (2006.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 39/0005 (2013.01); A61K 9/127 (2013.01); A61K 38/37 (2013.01); A61K 38/47 (2013.01); A61K 47/6911 (2017.08); C12Y 302/0102 (2013.01); A61K 2039/577 (2013.01); A61K 2039/6018 (2013.01);
Abstract
Methods and compositions to reduce immunogenicity of proteins are disclosed. Compositions comprising therapeutic proteins (such as Factor VIII or any other protein or peptide) complexed with liposomes comprising PS and PC (PS liposomes), or comprising PS, PI and PC and, optionally, cholesterol (PS/PI liposomes) may be used.