The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2018

Filed:

Feb. 04, 2014
Applicant:

Seres Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Geoffrey Von Maltzahn, Boston, MA (US);

Matthew R. Henn, Somerville, MA (US);

David N. Cook, Brooklyn, NY (US);

David Arthur Berry, Brookline, MA (US);

Noubar B. Afeyan, Lexington, MA (US);

Brian Goodman, Boston, MA (US);

Mary-Jane Lombardo McKenzie, Arlington, MA (US);

Marin Vulic, Boston, MA (US);

Assignee:

Seres Therapeutics, Inc., Cambridge, MA (US);

Attorney:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/741 (2015.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 9/48 (2006.01); A61K 35/74 (2015.01); C12N 1/20 (2006.01); A61K 35/742 (2015.01); A61K 35/744 (2015.01); A61K 35/745 (2015.01); A61K 35/747 (2015.01);
U.S. Cl.
CPC ...
A61K 35/741 (2013.01); A61K 9/0053 (2013.01); A61K 9/48 (2013.01); A61K 9/4816 (2013.01); A61K 35/74 (2013.01); A61K 35/742 (2013.01); A61K 35/744 (2013.01); A61K 35/745 (2013.01); A61K 35/747 (2013.01); A61K 45/06 (2013.01); C12N 1/20 (2013.01);
Abstract

Methods and compositions for populating the gastrointestinal tract of a subject are described. Methods include administering to a subject a therapeutic composition comprising a purified population of spore-forming bacteria produced by providing a fecal material and subjecting the material to a treatment step resulting in purification of spore-forming bacteria. Methods include administering an amount effective to engraft and/or augment in the gastrointestinal tract in order to treat or prevent a dysbiosis in the mammalian subject.


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