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For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10064850 B1

PDFFull Text
Date of Patent:
Sep. 04, 2018

Filed:

Aug. 08, 2016

Compositions and methods for prophylaxis and treatment of addictions

Applicant:

Omeros Corporation, Seattle, WA (US);

Inventor:

Roberto Ciccocioppo, Camerino, IT;

Assignee:

Omeros Corporation, Seattle, WA (US);

Attorney:

Marcia S. Kelbon

Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

Michael J Schmitt

Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/00 (2006.01); A61K 31/137 (2006.01); A61K 31/138 (2006.01); A61K 31/195 (2006.01); A61K 31/35 (2006.01); A61K 31/4015 (2006.01); A61K 31/4178 (2006.01); A61K 31/445 (2006.01); A61K 31/485 (2006.01); A61K 31/519 (2006.01); A61K 31/70 (2006.01); A61K 45/06 (2006.01); A61K 31/4184 (2006.01); A61K 31/425 (2006.01); A61K 31/135 (2006.01); A61K 31/197 (2006.01); A61K 31/426 (2006.01); A61K 31/4748 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/00 (2013.01); A61K 31/135 (2013.01); A61K 31/137 (2013.01); A61K 31/138 (2013.01); A61K 31/195 (2013.01); A61K 31/197 (2013.01); A61K 31/35 (2013.01); A61K 31/4015 (2013.01); A61K 31/4178 (2013.01); A61K 31/4184 (2013.01); A61K 31/425 (2013.01); A61K 31/426 (2013.01); A61K 31/445 (2013.01); A61K 31/4748 (2013.01); A61K 31/485 (2013.01); A61K 31/519 (2013.01); A61K 31/55 (2013.01); A61K 31/70 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention relates to methods of treating or preventing addiction and relapse use of addictive agents, and treating or preventing addictive or compulsive behavior and relapse practice of an addictive behavior or compulsion, by administering a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, alone or in combination with another therapeutic agent, such as, for example, an opioid receptor antagonist or an antidepressant, or an addictive agent, such as, for example, an opioid agonist. The present invention also includes pharmaceutical compositions for treating or preventing addiction or relapse that include a PPARγ agonist and one or more other therapeutic or addictive agents, as well as unit dosage forms of such pharmaceutical compositions, which contain a dosage effective in treating or preventing addiction or relapse. The methods and compositions of the invention are useful in the treatment or prevention of addiction to any agent, including alcohol, nicotine, marijuana, cocaine, and amphetamines, as well as compulsive and addictive behaviors, including pathological gambling and pathological overeating.

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