The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Aug. 11, 2015
Applicant:
Dongguk University Industry-academy Cooperation Foundation, Seoul, KR;
Inventors:
Gun Il Im, Gyeonggi-do, KR;
Mi Lan Kang, Seoul, KR;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/167 (2006.01); A61K 9/00 (2006.01); A61K 47/48 (2006.01); A61K 31/722 (2006.01); C08B 37/08 (2006.01); C08L 5/08 (2006.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 31/167 (2013.01); A61K 9/0019 (2013.01); A61K 31/722 (2013.01); A61K 47/48923 (2013.01); A61K 47/6927 (2017.08); A61K 47/6939 (2017.08); C08B 37/003 (2013.01); C08L 5/08 (2013.01);
Abstract
The present invention relates to kartogenin-conjugated chitosan particles with an improved sustained release property and biocompatibility. Effects of increases in biocompatibility, chondrogenic differentiation efficiency and retention time in the joints were confirmed by using kartogenin-chitosan microparticles or kartogenin-chitosan nanoparticles of the present invention, and thus targeted treatment, in the prevention or treatment of bone diseases, is enabled through a more fundamental approach.