The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2018
Filed:
Aug. 12, 2013
Applicant:
Medirista Biotechnologies Ab, Stockholm, SE;
Inventor:
Johan Frostegård, Stockholm, SE;
Assignee:
MEDIRISTA BIOTECHNOLOGIES AB, Stockholm, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); G01N 33/00 (2006.01); C07K 16/18 (2006.01); G01N 33/53 (2006.01); A61K 38/17 (2006.01); G01N 33/564 (2006.01); G01N 33/92 (2006.01); C07K 16/44 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5308 (2013.01); A61K 38/1709 (2013.01); C07K 16/18 (2013.01); C07K 16/44 (2013.01); G01N 33/564 (2013.01); G01N 33/92 (2013.01); C07K 2317/76 (2013.01); G01N 2800/104 (2013.01); G01N 2800/24 (2013.01); G01N 2800/2871 (2013.01); G01N 2800/32 (2013.01); G01N 2800/324 (2013.01); G01N 2800/50 (2013.01);
Abstract
Low levels of antibodies reactive with oxidized Cardiolipin (oxCL) in mammals are related to an increased risk of developing cardiovascular diseases, auto-immune diseases or inflammatory conditions. High levels can have a protective function and in general there is a negative association between manifestations of these conditions and antibodies against oxCL. Thus, based on their relations methods of monitoring, determining and diagnosing as well as methods of immunization and therapy of these diseases and conditions are provided.