The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2018

Filed:

Jan. 09, 2015
Applicant:

University of Delaware, Newark, DE (US);

Inventors:

Eleftherios T. Papoutsakis, Newark, DE (US);

Sergios Nicolaou, Larnaca, CY;

Alan Fast, Newark, DE (US);

Vasiliki Falara, Newark, DE (US);

Robert Kyle Bennett, Elkton, MD (US);

William Brian Whitaker, Newark, DE (US);

Nicholas Richard Sandoval, Newark, DE (US);

Jacqueline Gonzalez, Elkton, MD (US);

Maciek Antoniewicz, Baltimore, MD (US);

Assignee:

University of Delaware, Newark, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/32 (2006.01); C12P 7/16 (2006.01); C12P 7/40 (2006.01); C12P 7/42 (2006.01); C12P 7/44 (2006.01); C12P 7/46 (2006.01); C12P 7/62 (2006.01); C12N 9/04 (2006.01); C12N 9/88 (2006.01); C12N 9/90 (2006.01); C12N 15/52 (2006.01); C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
C12N 1/32 (2013.01); C12N 9/0006 (2013.01); C12N 9/88 (2013.01); C12N 9/90 (2013.01); C12N 15/52 (2013.01); C12N 15/70 (2013.01); C12P 7/16 (2013.01); C12P 7/40 (2013.01); C12P 7/42 (2013.01); C12P 7/44 (2013.01); C12P 7/46 (2013.01); C12P 7/625 (2013.01); Y02E 50/10 (2013.01);
Abstract

A non-naturally occurring microbe capable of growing in a medium comprising methanol is provided. The methanol contributes to a significant percentage (e.g., at least 40%) of the carbon source for the non-naturally occurring microbe, which expresses heterologous methanol dehydrogenase (MDH) and heterologous ribulose monophosphate (RuMP) pathway enzymes. Methods for producing liquid fuels and chemicals by the non-naturally occurring microbe and methods for preparing the non-naturally occurring microbe are also provided.


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