The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2018

Filed:

Dec. 23, 2014
Applicants:

Alk-abello A/s, Horsholm, DK;

LA Jolla Institute for Allergy and Immunology, La Jolla, CA (US);

Inventors:

Claus Lundegaard, Soborg, DK;

Lars Harder Christensen, Allerod, DK;

Peter Adler Wurtzen, Vedbaek, DK;

Alessandro Sette, La Jolla, CA (US);

John Sidney, San Diego, CA (US);

Gitte Lund, Allerod, DK;

Peter Sejer Andersen, Vanløse, DK;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); A61K 39/35 (2006.01);
U.S. Cl.
CPC ...
C07K 14/43531 (2013.01); A61K 39/35 (2013.01);
Abstract

The invention relates to combinations of peptides or variants thereof derived from a portion of an amino sequence of a house dust mite allergen, e.g. the allergens Der p 1, Der f 1, Der p 2 and/or Der f 2. Such peptides comprise at least one T cell epitope and a significant high number of patients in a worldwide population will have HLA alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by a dust mite.


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