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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10059681 B1

PDFFull Text
Date of Patent:
Aug. 28, 2018

Filed:

May. 27, 2016

Disubstituted maleic anhydrides with altered kinetics of ring closure

Applicant:

Arrowhead Madison Inc., Madison, WI (US);

Inventors:

Andrei V. Blokhin, Fitchburg, WI (US);

David B. Rozema, Cross Plains, WI (US);

Jonathan D. Benson, Stoughton, WI (US);

Jeffrey C. Carlson, Madison, WI (US);

Assignee:

Arrowhead Pharmaceuticals, Inc., Pasadena, CA (US);

Attorney:

Robert Michael Teigen

Primary Examiner:

Jonathan S Lau

Int. Cl.
CPC ...
C07D 307/66 (2006.01); C07H 15/08 (2006.01); C07H 15/26 (2006.01); C07D 307/89 (2006.01); C07D 307/60 (2006.01); C07D 307/88 (2006.01);
U.S. Cl.
CPC ...
C07D 307/89 (2013.01); C07D 307/60 (2013.01); C07D 307/66 (2013.01); C07D 307/88 (2013.01); C07H 15/08 (2013.01); C07H 15/26 (2013.01);
Abstract

We describe anhydride compounds suitable for physiologically labile modification of amine-containing molecules. The described anhydrides form reversible linkages having desirable kinetics for in vivo delivery of biologically active molecules. Also described are endosomolytic polymers formed by modification of membrane active polyamines with the described anhydrides.

Find Patent Forward Citations

Blokhin, Andrei. (2018). Disubstituted maleic anhydrides with altered kinetics of ring closure (U.S. Patent No. 10059681). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10059681

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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