The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2018
Filed:
Sep. 14, 2015
Applicant:
Children's Medical Center Corporation, Boston, MA (US);
Inventor:
Julian Blagg, Surrey, GB;
Assignee:
Children's Medical Center Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/14 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07D 209/12 (2006.01); C07D 209/16 (2006.01); C07D 209/18 (2006.01); C07C 235/06 (2006.01); C07C 311/37 (2006.01); C07C 317/32 (2006.01); C07D 213/73 (2006.01);
U.S. Cl.
CPC ...
C07D 209/14 (2013.01); C07C 235/06 (2013.01); C07C 311/37 (2013.01); C07C 317/32 (2013.01); C07D 209/12 (2013.01); C07D 209/16 (2013.01); C07D 209/18 (2013.01); C07D 213/73 (2013.01); C07D 401/12 (2013.01); C07D 413/12 (2013.01);
Abstract
Disclosed herein are small molecule heterocyclic inhibitors of sepiapterin reductase (SPR), and prodrugs and pharmaceutically acceptable salts thereof. The Also featured are pharmaceutical compositions of the compounds and uses of these compounds for the treatment or prevention of pain (e.g., inflammatory pain, nociceptive pain, functional pain, and neuropathic pain).