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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10058624 B1

PDFFull Text
Date of Patent:
Aug. 28, 2018

Filed:

Apr. 15, 2016

Recombinant promoters and vectors for protein expression in liver and use thereof

Applicants:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Inventors:

Christopher B. Doering, Atlanta, GA (US);

H. Trent Spencer, Atlanta, GA (US);

Harrison C. Brown, Atlanta, GA (US);

Assignees:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Attorney:

Klarquist Sparkman, LLP

Primary Examiner:

Kevin K Hill

Int. Cl.
CPC ...
C07K 14/745 (2006.01); C07K 14/755 (2006.01); C12N 15/85 (2006.01); A61K 48/00 (2006.01); C12N 7/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); C07K 14/755 (2013.01); C12N 7/00 (2013.01); C12N 15/85 (2013.01); C12Y 304/21022 (2013.01); A61K 38/00 (2013.01); C12N 2750/14132 (2013.01); C12N 2750/14143 (2013.01); C12N 2830/008 (2013.01);
Abstract

Disclosed herein are recombinant viral vectors comprising a liver specific promotor in operable combination with a heterologous nucleic acid sequence encoding a protein, such as a clotting factor. Methods of treating a subject with a clotting disorder, such as hemophilia A or hemophilia B, are also provided.

Find Patent Forward Citations

Doering, Christopher. (2018). Recombinant promoters and vectors for protein expression in liver and use thereof (U.S. Patent No. 10058624). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10058624

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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