The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2018
Filed:
Sep. 30, 2016
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Peter Dragovich, San Diego, CA (US);
Thomas Pillow, San Francisco, CA (US);
Jack Sadowsky, Dublin, CA (US);
Mark X. Sliwkowski, San Carlos, CA (US);
BinQing Wei, Belmont, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01); C07D 519/00 (2006.01); C07K 16/32 (2006.01); A61K 31/5517 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/5517 (2013.01); A61K 47/6803 (2017.08); A61K 47/6851 (2017.08); A61K 47/6855 (2017.08); A61K 47/6889 (2017.08); C07D 519/00 (2013.01); C07K 16/2803 (2013.01); C07K 16/32 (2013.01); C07K 2317/40 (2013.01); C07K 2317/522 (2013.01); C07K 2317/567 (2013.01);
Abstract
The invention provides antibody-drug conjugates comprising an antibody conjugated to a pyrrolobenzodiazepine drug moiety via a disulfide linker, pyrrolobenzodiazepine linker-drug intermediates, and methods of using the antibody-drug conjugates.