The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2018
Filed:
Jan. 05, 2017
Applicant:
Toshikazu Nakamura, Kyoto-shi, Kyoto, JP;
Inventors:
Assignee:
TOSHIKAZU NAKAMURA, Kyoto, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/18 (2006.01); A61K 49/00 (2006.01); C07K 14/475 (2006.01); C07K 14/48 (2006.01); C07K 14/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1833 (2013.01); A61K 48/00 (2013.01);
Abstract
The invention presents a therapeutic agent (and progress suppressant) for amyotrophic lateral sclerosis (ALS) containing HGF and/or HGF gene as active ingredient. HGF has an effect of improving the motor function of ALS and life span through two actions, that is, direct neuronutrient factor activity on motoneurons, and indirect improving action of glutamate cytotoxicity on motoneurons by maintaining the level of glutamate transporter in astrocytes. Hence, HGF and/or HGF gene can be used as an effective therapeutic agent not known in the past.