The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2018

Filed:

Dec. 06, 2017
Applicant:

Magenta Therapeutics Inc., Cambridge, MA (US);

Inventors:

Dwight Morrow, West Chester, PA (US);

Patrick C. Falahee, Somerville, MA (US);

Anthony Boitano, Newton, MA (US);

Michael P. Cooke, Brookline, MA (US);

Kevin A. Goncalves, Boston, MA (US);

Assignee:

Magenta Therapeutics, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A01N 65/00 (2009.01); C12N 5/071 (2010.01); A61K 35/28 (2015.01); A61K 31/4427 (2006.01); A61P 37/00 (2006.01); C12N 5/0789 (2010.01); A61K 45/06 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 31/4427 (2013.01); A61K 45/06 (2013.01); A61P 37/00 (2018.01); C12N 5/0647 (2013.01); A61K 2035/124 (2013.01);
Abstract

Described herein are compositions and methods useful for mobilizing populations of hematopoietic stem and progenitor cells within a subject, as well as for determining whether samples of mobilized cells are suitable for release for ex vivo expansion and/or therapeutic use. In accordance with the composition and methods described herein, mobilized hematopoietic stem and progenitor cells can be withdrawn from a donor and administered to a patient for the treatment of various disorders, including hematopoietic diseases, metabolic disorders, cancers, and autoimmune diseases, among others.


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