The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2018

Filed:

Jun. 21, 2017
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Ning Chen, Thousand Oaks, CA (US);

Xiaoqi Chen, Palo Alto, CA (US);

Yinhong Chen, Hayward, CA (US);

Zice Fu, Foster City, CA (US);

Julie Anne Heath, Chico, CA (US);

Daniel B. Horne, Natick, MA (US);

Matthew R. Kaller, Ventura, CA (US);

Aarif Yusuf Khakoo, Woodside, CA (US);

David John Kopecky, Studio City, CA (US);

Zhihua Ma, Lexington, MA (US);

Jeffrey T. Mihalic, San Francisco, CA (US);

Gayathri Swaminath, Brisbane, CA (US);

Xiaodong Wang, Johns Creek, GA (US);

Wen-Chen Yeh, Belmont, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/497 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/497 (2013.01); A61K 45/06 (2013.01);
Abstract

Methods of treating heart failure include administering to a subject having heart failure an effective amount of a triazole compound that is an agonist of the APJ receptor, a pharmaceutically acceptable salt of the compound, or a mixture thereof. Compounds particularly useful in such methods are provided herein.


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